Friday, March 29, 2024

NTAGI to soon chalk out roadmap to introduce Zydus Cadila’s vaccine in Covid inoculation drive

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By PTI

NEW DELHI: The National Technical Advisory Group on Immunisation (NTAGI) will soon hold a meeting to devise a roadmap for introducing Zydus Cadila’s Covid vaccine in the inoculation drive and prioritising beneficiaries focusing on those aged 12-18 years with comorbidities.

The indigenously developed world’s first DNA-based needle-free COVID-19 vaccine ZyCoV-D received Emergency Use Authorisation from the drug regulator on August 20 making it the first vaccine to be administered in the age group of 12-18 years in the country.

NTAGI Chairman Dr N K Arora said it is estimated that there are around 12 crore adolescents in the age group of 12-18 years in India and less than 1 per cent of them may have comorbidities.

​ALSO READ | Despite approval to Zydus Cadila vaccine, kids’ inoculation may not start anytime soon

“The NTAGI’s meeting will be held soon to chalk out a roadmap for introducing the three-dose ZyCoV-D vaccine in the ongoing COVID-19 vaccination drive.

The meeting will also focus on prioritisation of beneficiaries as this vaccine is approved for both adolescents and adults,” he said.

“The aim is to develop a priority list with the focus being on adolescents aged 12-18 years with comorbidities,” Dr Arora said.

The NTAGI will provide the protocol and framework for the introduction of this vaccine in the COVID-19 immunisation drive.

Covishield, Covaxin and Sputnik V vaccines are being given to only those above 18 years and unlike ZyCoV-D, which is three-dose, these are administered in two doses.

The Department of Biotechnology (DBT) has said that ZyCoV-D is the world’s first DNA-based vaccine against the coronavirus and when injected produces the spike protein of the SARS-CoV-2 virus and elicits an immune response, which plays a vital role in protection from the disease as well as viral clearance.

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It said that interim results from Phase-III clinical trials in over 28,000 volunteers showed primary efficacy of 66.6 per cent for symptomatic RT-PCR positive cases.

This has been the largest vaccine trial so far in India for COVID-19, the DBT said.

The vaccine had already exhibited robust immunogenicity and tolerability and safety profile in the adaptive Phase one and two clinical trials.

Both Phase one/two and Phase three clinical trials have been monitored by an independent data safety monitoring board, it added.

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